The Philippine Cobra’s habitat include low-lying plains and forested regions, along with open fields, grasslands, dense jungle, agricultural fields, and human settlements. This species of cobra is particularly fond of water, so it can be found very close to ponds, rivers, or large puddles of water.
This species feeds predominantly on small mammals, frogs, and even other snakes. Small rodents such as mice and small rats are their preferred prey and make up the majority of their diets. However, they will also eat other sizable snakes, small lizards, frogs, eggs, and when the opportunity arises, small birds and the venom of the Philippine Cobra is a potent postsynaptic neurotoxin which affects respiratory function and can cause neurotoxicity and respiratory paralysis, as the neurotoxins interrupt the transmission of nerve signals by binding to the neuromuscular junctions near the muscles.